Background: Peripheral artery disease (PAD) is associated with cardiovascular risk in type 2 diabetes mellitus (DM). The ankle-brachial index (ABI) is used for diagnosis of PAD. Objectives: Establish the prevalence and incidence rate for PAD and determine the associated factors and survival time for the development of PAD. Methods: Retrospective crosssectional cohort study (follow up: 10 years) in 578 DM patients with at least 1 ABI measurement in a primary level of care diabetes clinic. Data was collected from clinical records. Sociodemographic and laboratory variables were analyzed determining its association (mean difference and bivariate logistic regression). Survival was calculated through life tables and Kaplan-Meier analysis. Results: The prevalence of PAD was 13.98%. The incidence rate through the time of follow up was 23.38 per 1000 person-year (95% CI: 19.91-27.26). The group that developed PAD showed higher glycated hemoglobin levels (P =.025), more years of DM

Objective: To quantify the health-related quality of life (HRQoL) of patients with type 2 diabetes mellitus (DM) in Ecuador and to determine its association, or lack thereof, with demographic and clinical variables, particularly with the comorbidities and complications of DM. Methods: This was an analytical cross-sectional study with 325 patients attending regular care at a primary health care center in Quito, Ecuador. HRQoL was measured using the EuroQol 5-dimension 3-level (EQ-5D-3L) questionnaire. The patients were screened for diabetic nephropathy, retinopathy, and peripheral artery disease (PAD). Clinical files were reviewed to obtain data regarding gender, age, time since diagnosis, type of treatment, glycemic control, and history (if any) of hypertension and/or dyslipidemia. Associations were verified using the Mann–Whitney U or Kruskal–Wallis test, and the confounding effects of the variables “age” and “gender” were controlled for using logistic regression analysis. Results: The mean HRQoL for the population was 0.844 (±0.215) on the EQ-5D-3L index (EQ-Index) and 80.6 (±18.8) on the EQ visual analogue scale (EQ-VAS). The prevalence of DM complications was 1.8% for nephropathy, 14.8% for retinopathy, and 14.5% for PAD. Of the participating patients, 66.8% presented hypertension and 91.4%, dyslipidemia. Significant associations were found between lower scores on the EQ-Index and age (≥65 years) (0.84 vs. 0.87; p = 0.016), time since diagnosis (≥10 years) (0.81 vs. 0.87; p = 0.005), presence of hypertension (0.83 vs. 0.88; p = 0.017), and, after controlling for age and gender, presence of nephropathy.